User profiles for Jonathan Gubbay

Jonathan Gubbay

BC Children's Hospital and Women's Hospital; BC Centre for Disease Control
Verified email at cw.bc.ca
Cited by 11357

Diagnosing COVID-19: the disease and tools for detection

…, VYC Li, H Chen, S Mubareka, JB Gubbay… - ACS …, 2020 - ACS Publications
COVID-19 has spread globally since its discovery in Hubei province, China in December
2019. A combination of computed tomography imaging, whole genome sequencing, and …

[HTML][HTML] Acute myocardial infarction after laboratory-confirmed influenza infection

…, M Smieja, G Zahariadis, JB Gubbay - … England Journal of …, 2018 - Mass Medical Soc
Background Acute myocardial infarction can be triggered by acute respiratory infections.
Previous studies have suggested an association between influenza and acute myocardial …

[HTML][HTML] Effectiveness of COVID-19 vaccines against symptomatic SARS-CoV-2 infection and severe outcomes with variants of concern in Ontario

S Nasreen, H Chung, S He, KA Brown, JB Gubbay… - Nature …, 2022 - nature.com
SARS-CoV-2 variants of concern (VOC) are more transmissible and may have the potential
for increased disease severity and decreased vaccine effectiveness. We estimated the …

Estimated effectiveness of COVID-19 vaccines against Omicron or Delta symptomatic infection and severe outcomes

…, KA Brown, PC Austin, DB Fell, JB Gubbay… - JAMA network …, 2022 - jamanetwork.com
Importance The incidence of SARS-CoV-2 infection, including among individuals who have
received 2 doses of COVID-19 vaccine, increased substantially following the emergence of …

Effectiveness of BNT162b2 and mRNA-1273 covid-19 vaccines against symptomatic SARS-CoV-2 infection and severe covid-19 outcomes in Ontario, Canada: test …

…, K Wilson, KL Schwartz, KA Brown, JB Gubbay… - bmj, 2021 - bmj.com
Objective To estimate the effectiveness of mRNA covid-19 vaccines against symptomatic
infection and severe outcomes (hospital admission or death). Design Test negative design …

[HTML][HTML] Low 2012–13 influenza vaccine effectiveness associated with mutation in the egg-adapted H3N2 vaccine strain not antigenic drift in circulating viruses

…, JA Dickinson, K Fonseca, AL Winter, JB Gubbay… - PloS one, 2014 - journals.plos.org
Background Influenza vaccine effectiveness (VE) is generally interpreted in the context of
vaccine match/mismatch to circulating strains with evolutionary drift in the latter invoked to …

[HTML][HTML] Genetic variability of human respiratory syncytial virus A strains circulating in Ontario: a novel genotype with a 72 nucleotide G gene duplication

…, JT Nadarajah, A Li, SN Patel, DE Low, JB Gubbay - PloS one, 2012 - journals.plos.org
Human respiratory syncytial virus (HRSV) is the main cause of acute lower respiratory
infections in children under 2 years of age and causes repeated infections throughout life. We …

[HTML][HTML] The impact of the COVID-19 pandemic on influenza, respiratory syncytial virus, and other seasonal respiratory virus circulation in Canada: A population-based …

…, C Sevenhuysen, A Campigotto, JB Gubbay… - The Lancet Regional …, 2021 - thelancet.com
Background The ongoing coronavirus disease 2019 (COVID-19) pandemic has resulted in
implementation of public health measures worldwide to mitigate disease spread, including; …

[HTML][HTML] Evolutionary and structural analyses of SARS-CoV-2 D614G spike protein mutation now documented worldwide

…, MR Isabel, AR Eshaghi, SN Patel, JB Gubbay… - Scientific reports, 2020 - nature.com
The COVID-19 pandemic, caused by the Severe Acute Respiratory Syndrome Coronavirus
2 (SARS-CoV-2), was declared on March 11, 2020 by the World Health Organization. As of …

A perfect storm: impact of genomic variation and serial vaccination on low influenza vaccine effectiveness during the 2014–2015 season

…, JA Dickinson, M Krajden, JB Gubbay… - Clinical Infectious …, 2016 - academic.oup.com
Background. The 2014–2015 influenza season was distinguished by an epidemic of
antigenically-drifted A(H3N2) viruses and vaccine components identical to 2013–2014. We report …