[HTML][HTML] Selenium in the immune system

JR Arthur, RC McKenzie, GJ Beckett - The Journal of nutrition, 2003 - Elsevier
Selenium as an essential component of selenocysteine-containing protein is involved in most
aspects of cell biochemistry and function. As such, there is much potential for selenium to …

[HTML][HTML] Selenium and endocrine systems

GJ Beckett, JR Arthur - Journal of endocrinology, 2005 - joe.bioscientifica.com
The trace element selenium (Se) is capable of exerting multiple actions on endocrine systems
by modifying the expression of at least 30 selenoproteins, many of which have clearly …

Protection conferred by selenium deficiency against aflatoxin B1 in the rat is associated with the hepatic expression of an aldo-keto reductase and a glutathione S …

R McLeod, EM Ellis, JR Arthur, GE Neal, DJ Judah… - Cancer Research, 1997 - AACR
Fischer 344 rats fed on a diet that is deficient in selenium are more resistant to the
hepatocarcinogen aflatoxin B 1 (AFB 1 ) than those fed on a selenium-sufficient diet. Hepatic cytosol …

Leptin up‐regulates pro‐inflammatory cytokines in discrete cells within mouse colon

…, E Kelaiditi, N Hoggard, JR Arthur… - Journal of Cellular …, 2011 - Wiley Online Library
Dysregulation of leptin associated with obesity is implicated in obesity‐related colon cancer,
but mechanisms are elusive. Increased adiposity and elevated plasma leptin are associated …

Metallothionein overexpression and resistance to toxic stress

JH Beattie, HLH Owen, SM Wallace, JR Arthur… - Toxicology letters, 2005 - Elsevier
Metallothionein (MT) protects against the harmful effects of a wide spectrum of stress factors.
The most studied of these factors is cadmium, whose toxicity is reduced on sequestration by …

Effects of selenium and vitamin E status on plasma creatine kinase activity in calves

JR Arthur - The Journal of nutrition, 1988 - Elsevier
In four experiments, attempts were made to induce nutritional myopathy in calves given a
selenium- and vitamin E-deficient diet (<0.01 mg Se/kg, <2 mg total vitamin E/kg). In housed …

Insulin, leptin, and adiponectin receptors in colon: regulation relative to differing body adiposity independent of diet and in response to dimethylhydrazine

…, GG Duthie, JG Mercer, JR Arthur… - American Journal …, 2007 - journals.physiology.org
Obesity has recently become a focus of research to elucidate diet and lifestyle factors as
important risk factors for colon cancer. Altered levels of insulin, leptin, and adiponectin have …

Selenium status of cats in four regions of the world and comparison with reported incidence of hyperthyroidism in cats in those regions

DJ Foster, KL Thoday, JR Arthur, F Nicol… - American Journal of …, 2001 - Am Vet Med Assoc
Objective —To assess selenium (Se) status of cats in 4 regions of the world and to compare
results for Se status with reported incidence of hyperthyroidism in cats in those regions. …

Free radicals and calcium homeostasis: relevance to malignant hyperthermia?

GG Duthie, JR Arthur - Free Radical Biology and Medicine, 1993 - Elsevier
The regulation of intracellular free calcium ions (Ca 2+ ) in skeletal muscle at rest and
during contraction depends on mechanisms such as Na + Ca 2+ exchangers, Ca 2+ -ATPases, …

Selenoproteins in human thyroid tissues

P Zagrodzki, F Nicol, JR Arthur, M Słowiaczek - Biofactors, 2001 - Wiley Online Library
The aim of the present work was to clarify whether the activities of selenoenzymes can serve
as markers for different tumors or goiters, as classified by histological criteria. The following …