An ecological approach to reducing potentially inappropriate medication use: Canadian deprescribing network

…, B Farrell, J Shaw, S Morgan, J Trimble… - Canadian Journal on …, 2017 - cambridge.org
Polypharmacy is growing in Canada, along with adverse drug events and drug-related costs.
Part of the solution may be deprescribing, the planned and supervised process of dose …

Team approach to polypharmacy evaluation and reduction: study protocol for a randomized controlled trial

…, M Savelli, D Sherifali, H Siu, JÉ Tarride, J Trimble… - Trials, 2021 - Springer
Background Polypharmacy in older adults can be associated with negative outcomes including
falls, impaired cognition, reduced quality of life, and general and functional decline. It is …

Characteristics of frequent emergency department users in British Columbia, Canada: a retrospective analysis

…, BR Holroyd, E Grafstein, CM Hohl, J Trimble… - … Open Access Journal, 2021 - cmajopen.ca
Background: Frequent emergency department users disproportionately account for rising
health care costs. We aimed to characterize frequent emergency department users in British …

Team approach to polypharmacy evaluation and reduction: feasibility randomized trial of a structured clinical pathway to reduce polypharmacy

…, S Borhan, JA Templeton, L Thabane, J Trimble - Pilot and Feasibility …, 2023 - Springer
Background Polypharmacy is associated with poorer health outcomes in older adults. Other
than the associated multimorbidity, factors contributing to this association could include …

Identifying subgroups and risk among frequent emergency department users in British Columbia

…, E Grafstein, CM Hohl, J Trimble… - Journal of the …, 2021 - Wiley Online Library
Objective: Frequent emergency department (ED) users are heterogeneous. We aimed to
identify subgroups and assess their mortality. Methods: We identified patients ≥18 years with ≥…

Reducing unnecessary urine culture testing in residents of long term care facilities

KL Piggott, J Trimble, JA Leis - bmj, 2023 - bmj.com
… This article was co-authored by Johanna Trimble, a dedicated caregiver of a patient who
has experienced adverse drug effects and unnecessary polypharmacy. Johanna is a published …

'I think this medicine actually killed my wife': patient and family perspectives on shared decision-making to optimize medications and safety

…, J Parascandalo, G Stephen, J Trimble - … Advances in Drug …, 2019 - journals.sagepub.com
Background: This study explored the perspectives and experiences from patients and
families around how patient/family preferences and priorities are considered in medication-related …

People who make frequent emergency department visits based on persistence of frequent use in Ontario and Alberta: a retrospective cohort study

…, CM Hohl, E Grafstein, F O'Sullivan, J Trimble… - … Open Access Journal, 2022 - cmajopen.ca
Background: The factors that underlie persistent frequent visits to the emergency department
are poorly understood. This study aimed to characterize people who visit emergency …

Theoretical underpinnings of a model to reduce polypharmacy and its negative health effects: Introducing the Team Approach to Polypharmacy Evaluation and …

…, JA Templeton, J Salerno, H Siu, J Trimble… - Drugs & Aging, 2023 - Springer
Background Polypharmacy, particularly among older adults, is gaining recognition as an
important risk to health. The harmful effects on health arise from disease–drug and drug–drug …

Strategies to promote public engagement around deprescribing

JP Turner, J Currie, J Trimble… - … advances in drug …, 2018 - journals.sagepub.com
Many seniors remain unaware that certain medications may be harmful, despite high rates
of polypharmacy and inappropriate medication use among community-dwelling older adults. …