[HTML][HTML] A systematic review of global surgery partnerships and a proposed framework for sustainability

N Jedrzejko, J Margolick, JH Nguyen… - Canadian Journal of …, 2021 - ncbi.nlm.nih.gov
Background: Building surgical capacity through global surgery partnerships (GSPs) between
high and low-and middle-income countries (LMICs) is a rising global health focus. Our aim …

Adherence to recommendations at a Canadian tertiary care Family Travel Clinic-A single centre analysis

EKK Fong, LG Pell, A Faress, JH Nguyen… - Travel Medicine and …, 2020 - Elsevier
Background Infectious and non-infectious risks associated with international travel can be
reduced with adherence to pre-travel advice from practitioners trained in travel medicine. …

Underestimation of travel-associated risks by adult and paediatric travellers compared to expert assessment: a cross-sectional study at a hospital-based family pre …

PP Piché-Renaud, JH Nguyen, LG Pell, XW Ma… - Travel Medicine and …, 2022 - Elsevier
Background Travellers' perception of their risk for acquiring travel-related conditions is an
important contributor to decisions and behaviors during travel. In this study, we aimed to …

[HTML][HTML] Postoperative outcomes for Nunavut Inuit at a Canadian quaternary care centre: a retrospective cohort study

JA McVicar, J Hoang-Nguyen, J O'Shea… - … Open Access Journal, 2022 - cmajopen.ca
Background: Structural aspects of health care systems, such as limited access to specialized
surgical and perioperative care, can negatively affect the outcomes and resource use of …

Study on activity of LRR-RLK VIII promoter driven arsenic tolerance in Arabidopsis model plant

NTT Quỳnh, NH Hoàng, HJ Hoang - Vietnam Journal of Biotechnology, 2016 - vjs.ac.vn
The Leucine-rich repeat receptor-like kinase (LRR-RLK), that is a receptor-like kinase
consists of leucine rich repeat fragments, plays an important role in the plant growth and …

Genome-wide association study identifies 30 loci associated with bipolar disorder

EA Stahl, G Breen, AJ Forstner, A McQuillin, S Ripke… - Nature …, 2019 - nature.com
Bipolar disorder is a highly heritable psychiatric disorder. We performed a genome-wide
association study (GWAS) including 20,352 cases and 31,358 controls of European descent, …

Allele-selective transcriptional repression of mutant HTT for the treatment of Huntington's disease

B Zeitler, S Froelich, K Marlen, DA Shivak, Q Yu, D Li… - Nature medicine, 2019 - nature.com
Huntington’s disease (HD) is a dominantly inherited neurodegenerative disorder caused by
a CAG trinucleotide expansion in the huntingtin gene (HTT), which codes for the pathologic …

Preclinical and clinical evaluation of the LRRK2 inhibitor DNL201 for Parkinson's disease

D Jennings, S Huntwork-Rodriguez, AG Henry… - Science translational …, 2022 - science.org
Mutations in leucine-rich repeat kinase 2 (LRRK2) are the most common genetic risk factors
for Parkinson’s disease (PD). Increased LRRK2 kinase activity is thought to impair …

[HTML][HTML] Interview language: a proxy measure for acculturation among Asian Americans in a population-based survey

S Lee, HA Nguyen, J Tsui - Journal of immigrant and minority health, 2011 - Springer
We examined health status and access to care among Asian Americans by the following
acculturation indicators: nativity, percent lifetime in the US, self-rated English proficiency, and …

[PDF][PDF] Rescue of a lysosomal storage disorder caused by Grn loss of function with a brain penetrant progranulin biologic

T Logan, MJ Simon, A Rana, GM Cherf, A Srivastava… - Cell, 2021 - cell.com
GRN mutations cause frontotemporal dementia (GRN-FTD) due to deficiency in progranulin
(PGRN), a lysosomal and secreted protein with unclear function. Here, we found that Grn –/– …