Importance Identifying asymptomatic individuals at high risk of impending cognitive decline
because of Alzheimer disease is crucial for successful prevention of dementia. Vascular risk …

Obsessive compulsive disorder (OCD) and major depressive disorder (MDD) are common,
often refractory, neuropsychiatric conditions for which new treatment approaches are urgently …

Importance In the absence of disease-modifying therapies for Alzheimer disease, there is a
critical need to identify modifiable risk factors that may delay the progression of Alzheimer …

Introduction Few studies have examined memory decline among patients with type 2 diabetes
using different oral hypoglycemic drugs. Methods Participants with normal cognition (NC) …

Objectives Amyloid‐beta (Aβ) and tau pathologies are commonly observed among clinically
normal older individuals at postmortem and can now be detected with in vivo neuroimaging. …

Importance Mounting evidence suggests that sex differences exist in the pathologic trajectory
of Alzheimer disease. Previous literature shows elevated levels of cerebrospinal fluid tau in …

Introduction Our objective was to investigate the effect of sex on cognitive decline within the
context of amyloid β (Aβ) burden and apolipoprotein E genotype. Methods We analyzed sex-…

There is an inconsistency regarding the relationship between thinking about personal past
experiences during autobiographical memory (AM) and thinking about other people's mental …

Background: Black Americans are approximately twice as likely to develop dementia as
compared to White Americans and the magnitude of this disparity is often attributed to a variety …

Objective Neuropathological studies have demonstrated that cerebrovascular disease and
Alzheimer disease (AD) pathology frequently co‐occur in older adults. The extent to which …