[HTML][HTML] Cardiac-resynchronization therapy for mild-to-moderate heart failure

…, DH Birnie, JL Sapp, R Yee, JS Healey… - … England Journal of …, 2010 - Mass Medical Soc
Background Cardiac-resynchronization therapy (CRT) benefits patients with left ventricular
systolic dysfunction and a wide QRS complex. Most of these patients are candidates for an …

Benefit of oral anticoagulant over antiplatelet therapy in atrial fibrillation depends on the quality of international normalized ratio control achieved by centers and …

…, P Commerford, MG Franzosi, JS Healey, S Yusuf - Circulation, 2008 - Am Heart Assoc
Background— Oral anticoagulation (OAC) therapy is effective in atrial fibrillation but requires
vigilance to maintain the international normalized ratio in the therapeutic range. This report …

Radiofrequency ablation vs antiarrhythmic drugs as first-line treatment of paroxysmal atrial fibrillation (RAAFT-2): a randomized trial

…, J Champagne, LD Sterns, H Beresh, JS Healey… - Jama, 2014 - jamanetwork.com
Importance Atrial fibrillation (AF) is the most common rhythm disorder seen in clinical practice.
Antiarrhythmic drugs are effective for reduction of recurrence in patients with symptomatic …

Screening for atrial fibrillation: a report of the AF-SCREEN International Collaboration

B Freedman, J Camm, H Calkins, JS Healey… - Circulation, 2017 - Am Heart Assoc
Approximately 10% of ischemic strokes are associated with atrial fibrillation (AF) first diagnosed
at the time of stroke. Detecting asymptomatic AF would provide an opportunity to prevent …

Systematic assessment of patients with unexplained cardiac arrest: Cardiac Arrest Survivors with Preserved Ejection Fraction Registry (CASPER)

AD Krahn, JS Healey, V Chauhan, DH Birnie… - Circulation, 2009 - Am Heart Assoc
Background— Cardiac arrest without evident cardiac disease may be caused by subclinical
genetic conditions. Provocative testing to unmask a phenotype is often necessary to detect …

A comparison of single-lead atrial pacing with dual-chamber pacing in sick sinus syndrome

…, JH Svendsen, WD Toff, JS Healey… - European heart …, 2011 - academic.oup.com
Aims In patients with sick sinus syndrome, bradycardia can be treated with a single-lead
pacemaker or a dual-chamber pacemaker. Previous trials have revealed that pacing modes …

[HTML][HTML] Subclinical atrial fibrillation and the risk of stroke

JS Healey, SJ Connolly, MR Gold… - New England journal …, 2012 - Mass Medical Soc
Background One quarter of strokes are of unknown cause, and subclinical atrial fibrillation
may be a common etiologic factor. Pacemakers can detect subclinical episodes of rapid atrial …

Cardiovascular outcomes with atrial-based pacing compared with ventricular pacing: meta-analysis of randomized trials, using individual patient data

JS Healey, WD Toff, GA Lamas, HR Andersen… - Circulation, 2006 - Am Heart Assoc
Background— Several randomized trials have compared atrial-based (dual-chamber or atrial)
pacing with ventricular pacing in patients with bradycardia. No trial has shown a mortality …

Rationale and design of the apixaban for the reduction of thrombo-embolism in patients with device-detected sub-clinical atrial fibrillation (ARTESiA) trial

…, GH Mairesse, P Mabo, AJ Camm, JS Healey - American heart …, 2017 - Elsevier
Background Device-detected subclinical atrial fibrillation (AF) refers to infrequent, short-lasting,
asymptomatic AF that is detected only with long-term continuous monitoring. Subclinical …

Risk of bleeding with 2 doses of dabigatran compared with warfarin in older and younger patients with atrial fibrillation: an analysis of the randomized evaluation of …

…, JS Healey, J Oldgren, S Yang, M Alings, S Kaatz… - Circulation, 2011 - Am Heart Assoc
Background— Dabigatran 150 and 110 mg twice a day and warfarin are effective for stroke
prevention in atrial fibrillation. The purpose of this study was to compare their risks of …