[HTML][HTML] 2006 Canadian clinical practice guidelines on the management and prevention of obesity in adults and children [summary]
DCW Lau, JD Douketis, KM Morrison, IM Hramiak… - Cmaj, 2007 - Can Med Assoc
Obesity is now reaching epidemic proportions in both developed and developing countries
and is affecting not only adults but also children and adolescents. Over the last 20 years, …
and is affecting not only adults but also children and adolescents. Over the last 20 years, …
Effect of intensive treatment of hyperglycaemia on microvascular outcomes in type 2 diabetes: an analysis of the ACCORD randomised trial
…, D Simmons, H Taylor, A Thomas, D Weiss, I Hramiak - The Lancet, 2010 - thelancet.com
Background Hyperglycaemia is associated with increased risk of cardiovascular complications
in people with type 2 diabetes. We investigated whether reduction of blood glucose …
in people with type 2 diabetes. We investigated whether reduction of blood glucose …
Albiglutide and cardiovascular outcomes in patients with type 2 diabetes and cardiovascular disease (Harmony Outcomes): a double-blind, randomised placebo …
…, R Enns, I Sinay, C Mathieu, V Yordanov, I Hramiak… - The Lancet, 2018 - thelancet.com
Background Glucagon-like peptide 1 receptor agonists differ in chemical structure, duration
of action, and in their effects on clinical outcomes. The cardiovascular effects of once-weekly …
of action, and in their effects on clinical outcomes. The cardiovascular effects of once-weekly …
Cardiovascular and metabolic effects of metformin in patients with type 1 diabetes (REMOVAL): a double-blind, randomised, placebo-controlled trial
…, N Greenlaw, T Tillin, I Hramiak… - The lancet Diabetes & …, 2017 - thelancet.com
Background Metformin might reduce insulin requirement and improve glycaemia in patients
with type 1 diabetes, but whether it has cardiovascular benefits is unknown. We aimed to …
with type 1 diabetes, but whether it has cardiovascular benefits is unknown. We aimed to …
Allogenic fecal microbiota transplantation in patients with nonalcoholic fatty liver disease improves abnormal small intestinal permeability: a randomized control trial
…, J Silverman, K Qumosani, I Hramiak… - Official journal of the …, 2020 - journals.lww.com
METHODS: Twenty-one patients with NAFLD were recruited and randomized in a ratio of 3:
1 to either an allogenic (n= 15) or an autologous (n= 6) FMT delivered by using an …
1 to either an allogenic (n= 15) or an autologous (n= 6) FMT delivered by using an …
Efficacy and safety of dapagliflozin in patients with inadequately controlled type 1 diabetes (DEPICT-1): 24 week results from a multicentre, double-blind, phase 3 …
…, V Woo, B St-Pierre, R Dumas, I Hramiak… - The lancet Diabetes & …, 2017 - thelancet.com
Background Dapagliflozin is a sodium-glucose cotransporter-2 inhibitor approved for the
treatment of type 2 diabetes. We aimed to assess the efficacy and safety of dapagliflozin as an …
treatment of type 2 diabetes. We aimed to assess the efficacy and safety of dapagliflozin as an …
A randomized trial of a home system to reduce nocturnal hypoglycemia in type 1 diabetes
…, BA Buckingham, HP Chase, I Hramiak… - Diabetes …, 2014 - Am Diabetes Assoc
OBJECTIVE Overnight hypoglycemia occurs frequently in individuals with type 1 diabetes
and can result in loss of consciousness, seizure, or even death. We conducted an in-home …
and can result in loss of consciousness, seizure, or even death. We conducted an in-home …
A modified protocol for estimation of insulin sensitivity with the minimal model of glucose kinetics in patients with insulin-dependent diabetes
DT FINEGOOD, IM HRAMIAK… - The Journal of Clinical …, 1990 - academic.oup.com
An exogenous insulin administration-modified, frequently sampled iv glucose tolerance test (FSIGT)
for application in insulin-dependent diabetic patients (IDDM) to allow for estimation …
for application in insulin-dependent diabetic patients (IDDM) to allow for estimation …
Predictive low-glucose insulin suspension reduces duration of nocturnal hypoglycemia in children without increasing ketosis
…, RP Wadwa, DM Wilson, T Ly, T Aye, I Hramiak… - Diabetes …, 2015 - Am Diabetes Assoc
OBJECTIVE Nocturnal hypoglycemia can cause seizures and is a major impediment to tight
glycemic control, especially in young children with type 1 diabetes. We conducted an in-…
glycemic control, especially in young children with type 1 diabetes. We conducted an in-…
Glucagon-like peptide I reduces postprandial glycemic excursions in IDDM
J Dupre, MT Behme, IM Hramiak, P McFarlane… - Diabetes, 1995 - Am Diabetes Assoc
Effects of human glucagon-like peptide I (GLP-I)(7–36)amide were examined in volunteers
having insulin-dependent diabetes mellitus (IDDM) with residual C-peptide (CP) secretion (n …
having insulin-dependent diabetes mellitus (IDDM) with residual C-peptide (CP) secretion (n …
