Systematic reviews are difficult to keep up to date, but failure to do so leads to a decay in
review currency, accuracy, and utility. We are developing a novel approach to systematic …

Problem/Condition: Hysterectomy is the second most frequently performed surgical procedure,
after cesarean section, for women of reproductive age in the United States. Approximately …

New approaches to evidence synthesis, which use human effort and machine automation in
mutually reinforcing ways, can enhance the feasibility and sustainability of living systematic …

While it is important for the evidence supporting practice guidelines to be current, that is
often not the case. The advent of living systematic reviews has made the concept of “living …

Objective: To determine the prevalence of peptic ulcer disease, irritable bowel syndrome (IBS)
and chronic constipation in two Iranian populations (pastoral nomads and industrial …

Objective: This systematic review critically evaluated clinical practice guidelines (CPGs) for
treating adults with major depressive disorder, dysthymia, or subthreshold or minor …

Background Previous systematic reviews have found limited evidence for the effectiveness
of pharmacological and psychological interventions for the management of depression in …

A living systematic review (LSR) should keep the review current as new research evidence
emerges. Any meta-analyses included in the review will also need updating as new material …

Purpose: This report updates the Cancer Care Ontario Program in Evidence-Based Care
guideline for the management of depression in adult patients with cancer. This guideline …

Objective Lobectomy is a standard treatment for stage I non–small cell lung cancer, but a
significant proportion of patients are considered at high risk for complications, including …