Background Nutrition guidelines recommendations differ on the use of parenteral nutrition (PN),
and existing clinical trial data are inconclusive. Our recent observational data show that …

Over the past several years, continuous venovenous hemodiafiltration (CVVHDF) using
pump-driven devices has gained wide acceptance as a form of renal replacement therapy for …

Background: Clinical data on patients admitted to hospital with coronavirus disease 2019 (COVID-19)
provide clinicians and public health officials with information to guide practice and …

This clinical practice guideline is intended for use in the care of both neurologically deceased
adult and pediatric potential organ donors. We based our recommendations on organ …

BACKGROUND Patients with acute traumatic cervical or high thoracic level spinal cord injury
(SCI) typically require mechanical ventilation (MV) during their acute admission. Placement …

Purpose Canadian donor management practices have not been reported. Our aim was to
inform clinicians and other stakeholders about the range of current practices. Methods This …

Background Nimodipine improves outcomes following aneurysmal subarachnoid hemorrhage
(aSAH). Guidelines recommend that all patients should receive a fixed-dose nimodipine …

Background COVID-19 is primarily known as a respiratory illness; however, many patients
present to hospital without respiratory symptoms. The association between non-respiratory …

Rationale: Limited information exists about the epidemiology, outcomes, and predictors of
weaning from mechanical ventilation in patients with spinal cord injury. Objectives: Our aim …

Background The LOVIT (Lessening Organ Dysfunction with Vitamin C) trial is a blinded
multicenter randomized clinical trial comparing high-dose intravenous vitamin C to placebo in …