Background: Hyperglycemia is associated with increased mortality in critically ill patients.
Randomized trials of intensive insulin therapy have reported inconsistent effects on mortality …

Background Septic shock is associated with vasopressin deficiency and a hypersensitivity to
its exogenous administration. The goal of the current study was to determine whether short-…

Objective Assess the risk of complications during endotracheal intubation (ETI) and their
association with the skill level of the intubating physician. Design Prospective cohort study of …

Objective: To review all cases of septic shock treated with vasopressin to determine the effects
on hemodynamic and renal function and to document any adverse effects. Setting: A 14-…

BACKGROUND: Pandemic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
is associated with high intensive care unit (ICU) mortality. We aimed to describe the clinical …

Objective Brain injury remains the leading cause of death in cases of trauma in North
America and Europe. This article critically appraised and summarised all published and peer-…

Introduction The critical care management of traumatic brain injury focuses on preventing
secondary ischemic injury. Cerebral oxygen delivery is dependent upon the cerebral perfusion …

… Address requests for reprints to: Dean R. Chittock, MD, MS, FRCPC, Critical Care
Medicine, Vancouver Hospital & Health Sciences Centre, Suite 360, Echlon Building, 855 …

Study objectives Individual comparison of cardiac output via intermittent thermodilution and
Fick technique over a wide range of cardiac outputs. Design Prospective clinical investigation…

Introduction The optimal glucose range in patients with severe traumatic brain injury (TBI)
remains unclear. The goal of this study was to examine the association of serum glucose …