User profiles for David Conen

David Conen

McMaster University, Hamilton Canada
Verified email at mcmaster.ca
Cited by 28637

Apixaban for stroke prevention in subclinical atrial fibrillation

…, G Boriani, AJ Camm, D Conen… - … England Journal of …, 2024 - Mass Medical Soc
Background Subclinical atrial fibrillation is short-lasting and asymptomatic and can usually
be detected only by long-term continuous monitoring with pacemakers or defibrillators. …

Meta-analysis identifies six new susceptibility loci for atrial fibrillation

…, M Kubo, UB Tedrow, LM Rose, PM Ridker, D Conen… - Nature …, 2012 - nature.com
Atrial fibrillation is a highly prevalent arrhythmia and a major risk factor for stroke, heart failure
and death 1 . We conducted a genome-wide association study (GWAS) in individuals of …

Screening for atrial fibrillation: a report of the AF-SCREEN International Collaboration

…, J Brachmann, A Brandes, TF Chao, D Conen… - Circulation, 2017 - Am Heart Assoc
Approximately 10% of ischemic strokes are associated with atrial fibrillation (AF) first diagnosed
at the time of stroke. Detecting asymptomatic AF would provide an opportunity to prevent …

Multi-ethnic genome-wide association study for atrial fibrillation

…, IE Christophersen, MK Chung, JW Cole, D Conen… - Nature …, 2018 - nature.com
Atrial fibrillation (AF) affects more than 33 million individuals worldwide 1 and has a complex
heritability 2 . We conducted the largest meta-analysis of genome-wide association studies (…

[HTML][HTML] Tranexamic acid in patients undergoing noncardiac surgery

…, M Marcucci, TW Painter, D Conen… - … England Journal of …, 2022 - Mass Medical Soc
Background Perioperative bleeding is common in patients undergoing noncardiac surgery.
Tranexamic acid is an antifibrinolytic drug that may safely decrease such bleeding. Methods …

[HTML][HTML] Prevalence of hyperuricemia and relation of serum uric acid with cardiovascular risk factors in a developing country

D Conen, V Wietlisbach, P Bovet, C Shamlaye… - BMC public health, 2004 - Springer
Background The prevalence of hyperuricemia has rarely been investigated in developing
countries. The purpose of the present study was to investigate the prevalence of hyperuricemia …

The long-and short-term impact of elevated body mass index on the risk of new atrial fibrillation: the WHS (Women's Health Study)

UB Tedrow, D Conen, PM Ridker, NR Cook… - Journal of the American …, 2010 - jacc.org
Objectives : The purpose of this study was to characterize the relationship between changes
in body mass index (BMI) and incident atrial fibrillation (AF) in a large cohort of women. …

Trans-ethnic association study of blood pressure determinants in over 750,000 individuals

…, RA Scott, C Langenberg, NJ Wareham, D Conen… - Nature …, 2019 - nature.com
In this trans-ethnic multi-omic study, we reinterpret the genetic architecture of blood
pressure to identify genes, tissues, phenomes and medication contexts of blood pressure …

Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation

…, O Melander, RJF Loos, J Laurikka, D Conen… - Nature …, 2017 - nature.com
Atrial fibrillation affects more than 33 million people worldwide and increases the risk of
stroke, heart failure, and death 1 , 2 . Fourteen genetic loci have been associated with atrial …

Dabigatran in patients with myocardial injury after non-cardiac surgery (MANAGE): an international, randomised, placebo-controlled trial

…, A Patel, K Gregus, K Lawrence, L Doharris, D Conen… - The Lancet, 2018 - thelancet.com
Background Myocardial injury after non-cardiac surgery (MINS) increases the risk of
cardiovascular events and deaths, which anticoagulation therapy could prevent. Dabigatran …