BACKGROUND: Cancer projections to the current year help in policy development, planning
of programs and allocation of resources. We sought to provide an overview of the expected …

OBJECTIVES: Irritable bowel syndrome (IBS) is a common disorder and available therapies
have limited efficacy. Mucosal inflammation and alterations in gut microflora may contribute …

Irritable bowel syndrome (IBS) is a highly prevalent, chronic disorder that significantly
reduces patients' quality of life. Advances in diagnostic testing and in therapeutic options for …

Background In order to review the epidemiologic evidence concerning previous lung diseases
as risk factors for lung cancer, a meta-analysis and systematic review was conducted. …

Background: Chronic kidney disease is an important risk factor for death and cardiovascular-related
morbidity, but estimates to date of its prevalence in Canada have generally been …

Background & Aims Despite the widespread increase in the incidence of early-onset colorectal
cancer (EoCRC), the reasons for this increase remain unclear. The objective of this study …

Background Population-based cancer screening can reduce cancer burden but was interrupted
temporarily due to the COVID-19 pandemic. We estimated the long-term clinical impact …

To clarify the role of previous lung diseases (chronic bronchitis, emphysema, pneumonia, and
tuberculosis) in the development of lung cancer, the authors conducted a pooled analysis …

Recent genome-wide association studies (GWASs) have identified common genetic variants
at 5p15.33, 6p21–6p22 and 15q25.1 associated with lung cancer risk. Several other …

Background: Regular cancer surveillance is crucial for understanding where progress is being
made and where more must be done. We sought to provide an overview of the expected …