Neonatal sepsis in low-income countries: epidemiology, diagnosis and prevention
CR Popescu, MMM Cavanagh, B Tembo… - Expert review of anti …, 2020 - Taylor & Francis
Introduction: Sepsis accounts for up to one-third of neonatal deaths in the world each year.
The World Health Organization acknowledges neonatal sepsis as a major global health …
The World Health Organization acknowledges neonatal sepsis as a major global health …
[HTML][HTML] Hyperoxia exposure impairs nephrogenesis in the neonatal rat: role of HIF-1α
CR Popescu, MR Sutherland, A Cloutier, G Benoît… - PloS one, 2013 - journals.plos.org
Preterm neonates are exposed at birth to high oxygen concentrations relative to the intrauterine
environment. We have previously shown in a rat model that a hyperoxic insult results in …
environment. We have previously shown in a rat model that a hyperoxic insult results in …
Rethinking management of neonates at risk of sepsis
Comment 280 www. thelancet. com Vol 394 July 27, 2019 are often unavailable in these
settings, thus antibiotics can be started without measures to inform cessation of therapy. Non-…
settings, thus antibiotics can be started without measures to inform cessation of therapy. Non-…
DDIT4L regulates mitochondrial and innate immune activities in early life
…, C Cheung, JH Oh, E Ackermann, CR Popescu… - JCI …, 2024 - Am Soc Clin Investig
Pattern-Recognition Receptor responses are profoundly attenuated before the third
trimester of gestation, in the relatively low oxygen human fetal environment. However, the …
trimester of gestation, in the relatively low oxygen human fetal environment. However, the …
Verbal Autopsy to Assess Postdischarge Mortality in Children With Suspected Sepsis in Uganda
…, M Maina, R Carter, CR Popescu, R Daftary… - …, 2023 - publications.aap.org
BACKGROUND Reducing child mortality in low-income countries is constrained by a lack of
vital statistics. In the absence of such data, verbal autopsies provide an acceptable method …
vital statistics. In the absence of such data, verbal autopsies provide an acceptable method …
[HTML][HTML] Whole blood genome-wide transcriptome profiling and metagenomics next-generation sequencing in young infants with suspected sepsis in a low-and middle …
CR Popescu, B Tembo, R Chifisi… - Gates Open …, 2020 - ncbi.nlm.nih.gov
Conducting collaborative and comprehensive epidemiological research on neonatal sepsis
in low-and middle-income countries (LMICs) is challenging due to a lack of diagnostic tests. …
in low-and middle-income countries (LMICs) is challenging due to a lack of diagnostic tests. …
[HTML][HTML] Piezoelectric Biocomposites for Bone Grafting in Dentistry
In this research, Hydroxyapatite—Potassium, Sodium Niobate—Chitosan (HA-KNN-CSL)
biocomposites were synthesized, both as hydrogel and ultra-porous scaffolds, to offer two …
biocomposites were synthesized, both as hydrogel and ultra-porous scaffolds, to offer two …
[HTML][HTML] World Health Organization Danger Signs to predict bacterial sepsis in young infants: A pragmatic cohort study
O Akinseye, CR Popescu… - PLOS Global Public …, 2023 - journals.plos.org
Bacterial sepsis is generally a major concern in ill infants. To help triaging decisions by front-line
health workers in these situations, the World Health Organization (WHO) has …
health workers in these situations, the World Health Organization (WHO) has …
Outcomes related to respiratory syncytial virus with an abbreviated palivizumab regimen in children with congenital heart disease: a descriptive analysis
J Claydon, CR Popescu, L Shaiba… - … Open Access Journal, 2019 - cmajopen.ca
Background: It has been hypothesized that 4 doses of palivizumab, a neutralizing monoclonal
antibody against respiratory syncytial virus (RSV), administered during a fixed-date RSV …
antibody against respiratory syncytial virus (RSV), administered during a fixed-date RSV …
World Health Organization Danger Signs to predict bacterial sepsis in newborns: A pragmatic prospective cohort study
O Akinseye, CR Popescu, M Chiume-Kayuni, MA Irvine… - medRxiv, 2023 - medrxiv.org
Background The World Health Organization (WHO) has developed danger signs (DS) to
help front-line health workers triage interventions in children with severe illnesses. Our …
help front-line health workers triage interventions in children with severe illnesses. Our …