Objective: To assess anal oncogenic human papillomavirus (HPV) and anal cytology as
screening tests for detecting high-grade anal intraepithelial neoplasia (AIN 2+), as this is an …

Bloodstream infections (BSIs) represent a substantial mortality risk, yet most studies are limited
to select pathogens or populations. The aim of this study was to describe the population-…

Background Evaluating different approaches to identifying frail home care clients at heightened
risk for adverse health outcomes is an important but understudied area. Our objectives …

Background Antibiotic use is the strongest modifiable risk factor for the development of
Clostridioides difficile infection, but prescribers lack quantitative information on comparative risks …

Objective: To estimate long-term mortality following major burn injury compared with matched
controls. Summary Background Data: The effect of sustaining a major burn injury on long-…

A recent study reported an association between COVID-19 infection and new-onset diabetes
among people younger than 18 years in the US. 1 The resulting media coverage was …

Background The role of antibiotics in preventing urinary tract infection (UTI) in older adults is
unknown. We sought to quantify the benefits and risks of antibiotic prophylaxis among older …

Background: HIV-positive men with a history of anal-receptive intercourse are at risk for anal
cancer. We determined whether human papilloma virus (HPV) biomarkers were correlated …

Objective Selective reporting of antibiotic susceptibility test results may help guide appropriate
antibiotic prescribing, particularly for urinary tract infections. Our objective was to describe …

Importance Diagnostic imaging overuse in children evaluated in emergency departments (EDs)
is a potential target for reducing low-value care. Variation in practice patterns across …