Background Sensitivity analyses play a crucial role in assessing the robustness of the findings
or conclusions based on primary analyses of data in clinical trials. They are a critical way …

Objectif La reussite de tout processus de recherche s’ appuie en partie sur la capacite des
chercheurs atraduire un probleme clinique en question de recherche, une taˆche ardue pour …

Background We sought to determine if the publication of the Consolidated Standards of
Reporting Trials (CONSORT) 1 extension for abstracts in 2008 had led to an improvement in …

PURPOSE We report the final, protocol-specified analysis of overall survival (OS) in GOG-0218,
a phase III, randomized trial of bevacizumab in women with newly diagnosed ovarian, …

Background Systemic adjuvant treatment might mitigate the high risk of disease recurrence
in patients with resected stage IIC–III melanoma. The BRIM8 study evaluated adjuvant …

Objectives Our objectives were to analyse the effects of text messaging versus usual care in
improving adherence to antiretroviral therapy (ART) in people living with HIV using …

Background Physical activity is known to benefit many physiological processes, including
bone turnover. There are; however, currently no clinical guidelines regarding the most …

Background Experts recommend formulating a structured research question to guide the
research design. However, the basis for this recommendation has not been formally evaluated. …

Background The Systemic Immune-Inflammation Index (SII) is a quantitative measurement
of the systemic immune-inflammatory response in the human body. The SII has been shown …

Objective Randomised controlled trials (RCTs) are often considered as the gold standard
for assessing new health interventions. Patients are randomly assigned to receive an …