State-of-the-art imaging of acute stroke

A Srinivasan, M Goyal, FA Azri, C Lum - Radiographics, 2006 - pubs.rsna.org
Stroke is a leading cause of mortality and morbidity in the developed world. The goals of an
imaging evaluation for acute stroke are to establish a diagnosis as early as possible and to …

Mechanical thrombectomy in acute ischemic stroke: a systematic review

…, T Krings, LK Casaubon, N Sikich, C Lum… - Canadian Journal of …, 2016 - cambridge.org
Although intravenous thrombolysis increases the probability of a good functional outcome in
carefully selected patients with acute ischemic stroke, a substantial proportion of patients …

Prediction of haematoma growth and outcome in patients with intracerebral haemorrhage using the CT-angiography spot sign (PREDICT): a prospective observational …

…, A Kobayashi, JM Boulanger, C Lum… - The Lancet …, 2012 - thelancet.com
Background In patients with intracerebral haemorrhage (ICH), early haemorrhage expansion
affects clinical outcome. Haemostatic treatment reduces haematoma expansion, but fails to …

Safety and efficacy of NA-1 in patients with iatrogenic stroke after endovascular aneurysm repair (ENACT): a phase 2, randomised, double-blind, placebo-controlled …

…, C McDougall, T Gunnarsson, M Chow, C Lum… - The Lancet …, 2012 - thelancet.com
Background Neuroprotection with NA-1 (Tat-NR2B9c), an inhibitor of postsynaptic density-95
protein, has been shown in a primate model of stroke. We assessed whether NA-1 could …

Analysis of workflow and time to treatment on thrombectomy outcome in the endovascular treatment for small core and proximal occlusion ischemic stroke (ESCAPE) …

…, DF Frei, C Fanale, D Tampieri, J Teitelbaum, C Lum… - Circulation, 2016 - Am Heart Assoc
Background— The Endovascular Treatment for Small Core and Proximal Occlusion Ischemic
Stroke (ESCAPE) trial used innovative imaging and aggressive target time metrics to …

Canadian stroke best practice recommendations: secondary prevention of stroke, practice guidelines, update 2017

…, G Gubitz, J Habert, S Jaspers, C Lum… - … journal of stroke, 2018 - journals.sagepub.com
The 2017 update of The Canadian Stroke Best Practice Recommendations for the Secondary
Prevention of Stroke is a collection of current evidence-based recommendations intended …

Imaging atherosclerosis with hybrid [18F] fluorodeoxyglucose positron emission tomography/computed tomography imaging: what Leonardo da Vinci could not see

MS Cocker, B Mc Ardle, JD Spence, C Lum… - Journal of Nuclear …, 2012 - Elsevier
Prodigious efforts and landmark discoveries have led toward significant advances in our
understanding of atherosclerosis. Despite significant efforts, atherosclerosis continues globally …

Endovascular treatment for Small Core and Anterior circulation Proximal occlusion with Emphasis on minimizing CT to recanalization times (ESCAPE) trial …

…, A Poppe, D Tampieri, C Lum… - … Journal of Stroke, 2015 - journals.sagepub.com
ESCAPE is a prospective, multicenter, randomized clinical trial that will enroll subjects with
the following main inclusion criteria: less than 12 h from symptom onset, age > 18, baseline …

Intracerebral hematoma morphologic appearance on noncontrast computed tomography predicts significant hematoma expansion

…, I Dzialowski, A Czlonkowska, JM Boulanger, C Lum… - Stroke, 2015 - Am Heart Assoc
Background and Purpose— Hematoma expansion in intracerebral hemorrhage is associated
with higher morbidity and mortality. The computed tomography (CT) angiographic spot …

Acute ischemic stroke with tandem lesions: technical endovascular management and clinical outcomes from the ESCAPE trial

…, D Roy, AY Poppe, V Yang, C Lum… - Journal of …, 2018 - jnis.bmj.com
Background Tandem occlusions of the extracranial carotid and intracranial carotid or middle
cerebral artery have a particularly poor prognosis without treatment. Several management …