User profiles for Brian Chan

Brian T Chan

- Verified email at partners.org - Cited by 2565

Brian Chan

- Verified email at manchester.ac.uk - Cited by 1951

[HTML][HTML] Persistence and evolution of SARS-CoV-2 in an immunocompromised host

…, M Desjardins, LR Baden, BT Chan… - … England Journal of …, 2020 - Mass Medical Soc
SARS-CoV-2 in an Immunocompromised Host This letter describes an immunocompromised
patient who had persistent infection with SARS-CoV-2 over a period of months, despite …

Neutralization of severe acute respiratory syndrome coronavirus 2 omicron variant by sera from BNT162b2 or CoronaVac vaccine recipients

…, AWH Chu, WM Chan, JD Ip, BPC Chan… - Clinical Infectious …, 2022 - academic.oup.com
Background The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) omicron
variant, designated as a variant of concern by the World Health Organization, carries …

The hydrodynamics of water strider locomotion

DL Hu, B Chan, JWM Bush - nature, 2003 - nature.com
Water striders Gerridae are insects of characteristic length 1 cm and weight 10 dynes that
reside on the surface of ponds, rivers, and the open ocean 1 , 2 , 3 , 4 . Their weight is …

In urban and rural India, a standardized patient study showed low levels of provider training and huge quality gaps

…, A Holla, V Das, M Mohanan, D Tabak, B Chan - Health affairs, 2012 - healthaffairs.org
This article reports on the quality of care delivered by private and public providers of primary
health care services in rural and urban India. To measure quality, the study used …

Fungal pathogen reduces potential for malaria transmission

S Blanford, BHK Chan, N Jenkins, D Sim, RJ Turner… - Science, 2005 - science.org
Using a rodent malaria model, we found that exposure to surfaces treated with fungal
entomopathogens following an infectious blood meal reduced the number of mosquitoes able to …

Virulence and competitive ability in genetically diverse malaria infections

…, AR Wargo, AS Bell, BHK Chan… - Proceedings of the …, 2005 - National Acad Sciences
Explaining parasite virulence is a great challenge for evolutionary biology. Intuitively,
parasites that depend on their hosts for their survival should be benign to their hosts, yet many …

Parkinson's disease-linked human PARK9/ATP13A2 maintains zinc homeostasis and promotes α-Synuclein externalization via exosomes

SMY Kong, BKK Chan, JS Park, KJ Hill… - Human molecular …, 2014 - academic.oup.com
α-Synuclein plays a central causative role in Parkinson's disease (PD). Increased expression
of the P-type ATPase ion pump PARK9/ATP13A2 suppresses α-Synuclein toxicity in …

Using multiple trabecular micro-bypass stents in cataract patients to treat open-angle glaucoma

GW Belovay, A Naqi, BJ Chan, M Rateb… - Journal of Cataract & …, 2012 - Elsevier
PURPOSE: To evaluate the efficacy of multiple trabecular micro-bypass stents combined
with cataract surgery in patients with open-angle glaucoma (OAG) and cataract. SETTING: …

Rapid spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron subvariant BA. 2 in a single-source community outbreak

…, WM Chan, SMU Abdullah, BPC Chan… - Clinical Infectious …, 2022 - academic.oup.com
Background The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron
variant BA.2 sublineage has increased rapidly in Europe and Asia since January 2022. Here, …

Omicron variant susceptibility to neutralizing antibodies induced in children by natural SARS-CoV-2 infection or COVID-19 vaccine

LL Chen, GT Chua, L Lu, BPC Chan… - Emerging microbes & …, 2022 - Taylor & Francis
The novel SARS-CoV-2 Omicron variant may increase the risk of re-infection and vaccine
breakthrough infections as it possesses key mutations in the spike protein that affect …