Background: Cholinesterase inhibitors (ChEIs) are the only drugs marketed for the treatment
of Alzheimer's disease. Despite numerous randomized controlled trials, the efficacy and …

… Barbara Liu was the principal investigator and wrote the manuscript. Geoff Anderson was
involved in the data analysis and wrote the manuscript. Nicole Mittmann was involved in the …

Background Compensatory stepping and grasping reactions are prevalent responses to
sudden loss of balance and play a critical role in preventing falls. The ability to execute these …

The objective of this study is to identify gender‐related differences in the types of symptoms
and drugs reported to cause an adverse drug reaction. Patient data from the Sunnybrook …

Objective: The objective of this study was to determine utility scores for various chronic
conditions. Design and setting: This study is a descriptive analysis. Health Utilities Index (HUI) …

“Change-in-support” (CIS) balance-recovery reactions that involve rapid stepping or reaching
movements play a critical role in preventing falls; however, age-related deficits in the neuro…

Background Previous research investigating exercise as a means of falls prevention in older
adults has shown mixed results. Lack of specificity of the intervention may be an important …

Apathy is a common behavioral symptom of Alzheimer's disease (AD), being present in up
to 70% of patients. Apathy in AD and non-AD populations has been associated with …

INTRODUCTION: More than half of older adults (age ≥ 65 yr) have 2 or more high-burden
multimorbidity conditions (ie, highly prevalent chronic diseases, which are associated with …

Background older patients admitted to hospitals are at risk for hospital-acquired morbidity
related to immobility. The aim of this study was to implement and evaluate an evidence-based …