User profiles for Ashley Davidson

Ashley B. Davidson

University of British Columbia
Verified email at eos.ubc.ca
Cited by 82

Chromatin-level regulation of biosynthetic gene clusters

…, Y Reyes-Dominguez, AD Davidson… - Nature chemical …, 2009 - nature.com
Loss-of-function Aspergillus nidulans CclA, a Bre2 ortholog involved in histone H3 lysine 4
methylation, activated the expression of cryptic secondary metabolite clusters in A. nidulans. …

A Gene Cluster Containing Two Fungal Polyketide Synthases Encodes the Biosynthetic Pathway for a Polyketide, Asperfuranone, in Aspergillus nidulans

YM Chiang, E Szewczyk, AD Davidson… - Journal of the …, 2009 - ACS Publications
The genome sequencing of Aspergillus species including A. nidulans reveals that the products
of many of the secondary metabolism pathways in these fungi have not been elucidated. …

[PDF][PDF] Molecular genetic mining of the Aspergillus secondary metabolome: discovery of the emericellamide biosynthetic pathway

YM Chiang, E Szewczyk, T Nayak, AD Davidson… - Chemistry & biology, 2008 - cell.com
The recently sequenced genomes of several Aspergillus species have revealed that these
organisms have the potential to produce a surprisingly large range of natural products, many …

Identification and Characterization of the Asperthecin Gene Cluster of Aspergillus nidulans

…, YM Chiang, CE Oakley, AD Davidson… - Applied and …, 2008 - Am Soc Microbiol
The sequencing of Aspergillus genomes has revealed that the products of a large number
of secondary metabolism pathways have not yet been identified. This is probably because …

Characterization of the Aspergillus nidulans Monodictyphenone Gene Cluster

YM Chiang, E Szewczyk, AD Davidson… - Applied and …, 2010 - Am Soc Microbiol
Deletion of cclA, a component of the COMPASS complex of Aspergillus nidulans, results in
the production of monodictyphenone and emodin derivatives. Through a set of targeted …

Molecular genetic analysis of the orsellinic acid/F9775 gene cluster of Aspergillus nidulans

…, YM Chiang, E Szewczyk, AD Davidson… - Molecular …, 2010 - pubs.rsc.org
F-9775A and F-9775B are cathepsin K inhibitors that arise from a chromatin remodelling
deletant strain of Aspergillus nidulans. A polyketide synthase gene has been determined to be …

Effect of community population size on breast cancer screening, stage distribution, treatment use and outcomes

…, IA Olivotto, C Speers, S Chia, A Davidson… - Canadian journal of …, 2012 - Springer
Objective Residents of rural communities have decreased access to cancer screening and
treatments compared to urban residents, though use of resources and patient outcomes have …

Stage, treatment and outcomes for patients with breast cancer in British Columbia in 2002: a population-based cohort study

A Davidson, S Chia, R Olson, A Nichol… - … Open Access Journal, 2013 - cmajopen.ca
Background There are very few long-term Canadian data on breast cancer outcomes by
stage. We described the stage, treatment and outcomes of breast cancer at a population level …

Genetic cause of autosomal recessive hereditary nephropathy in the English Cocker Spaniel

AG Davidson, RJ Bell, GE Lees… - Journal of veterinary …, 2007 - Wiley Online Library
Background:Autosomal recessive hereditary nephropathy (ARHN) in the English Cocker
Spaniel is caused by a type IV collagen defect, but the underlying mutation is unknown. Animals…

Predictors of treatment response to multidisciplinary care for persistent symptoms after pediatric concussion

JA O'Neill, SC Rose, AM Davidson… - Developmental …, 2022 - Taylor & Francis
Purpose To assess which pediatric patients experiencing persistent post-concussive symptoms
(PCS) benefit most from multidisciplinary treatment including specialists in Neurology, …