Background: Systematic reviews of randomized, controlled trials in patients with influenza
suggest a lack of evidence about the effects of antiviral therapy on several patient-important …

Signals from TGF-β superfamily receptors are transduced to the nucleus by Smad proteins,
which transcriptionally activate target genes. In Caenorhabditis elegans, defects in a TGF-β-…

Ischemia/reperfusion (I/R) injury in organ transplantation significantly contributes to graft failure
and is untreatable using current approaches. I/R injury is associated with activation of the …

BACKGROUND: First-line treatment for Graves disease is frequently 18 months of antithyroid
medication (ATM). Controversy exists concerning the next best line of treatment for patients …

Sequencing is important for understanding the molecular epidemiology and viral evolution
of hepatitis C virus (HCV) infection. To date, there is little standardisation among sequencing …

Objectives Clinical skills expertise can be advanced through accessible and cost‐effective
video‐based observational practice activities. Previous findings suggest that the observation …

Recent studies have provided evidence for the effectiveness of using doxycycline (Doxy-PEP)
to prevent bacterial sexually transmissible infections (STI), namely chlamydia, gonorrhoea…

Background— Patients who undergo tricuspid annuloplasty during left-side heart valve surgery
have a poor postoperative clinical outcome. However, preoperative right ventricular (RV) …

Background— Ischemia/reperfusion injury is a major factor in graft quality and subsequent
function in the transplantation setting. We hypothesize that the process of RNA interference …

Background Cancer is the leading cause of death in the developed world, and yet healthcare
practitioners infrequently discuss goals of care (GoC) with hospitalized cancer patients. We …