Context Between March and July 2009, the largest number of confirmed cases of 2009
influenza A(H1N1) infection occurred in North America. Objective To describe characteristics, …

Background Recent trials have questioned the benefit of early parenteral nutrition in adults.
The effect of early parenteral nutrition on clinical outcomes in critically ill children is unclear. …

OBJECTIVE: To characterize the epidemiology of and identify risk factors for neonatal
cardiac surgery–associated acute kidney injury (CS-AKI) and determine its impact on clinical …

Introduction The timely provision of critical care to hospitalised patients at risk for cardiopulmonary
arrest is contingent upon identification and referral by frontline providers. Current …

Background The optimal hemoglobin threshold for erythrocyte transfusions in critically ill
children is unknown. We hypothesized that a restrictive transfusion strategy of using packed red …

Background Multiple organ dysfunction syndrome is more frequent than death in paediatric
intensive care units. Estimation of the severity of this syndrome could be a useful additional …

Background Hypothermia therapy improves survival and the neurologic outcome in animal
models of traumatic brain injury. However, the effect of hypothermia therapy on the …

The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has caused the
Coronavirus Disease 2019 (COVID-19) worldwide pandemic in 2020. In response, most …

Importance There is limited evidence that the use of severity of illness scores in pediatric
patients can facilitate timely admission to the intensive care unit or improve patient outcomes. …

Objectives To examine the quality of reporting of harms in systematic reviews, and to determine
the need for a reporting guideline specific for reviews of harms. Design Systematic review…