Perioperative normothermia to reduce the incidence of surgical-wound infection and shorten hospitalization
A Kurz, DI Sessler, R Lenhardt - New England Journal of …, 1996 - Mass Medical Soc
Background Mild perioperative hypothermia, which is common during major surgery, may
promote surgical-wound infection by triggering thermoregulatory vasoconstriction, which …
promote surgical-wound infection by triggering thermoregulatory vasoconstriction, which …
Supplemental perioperative oxygen to reduce the incidence of surgical-wound infection
Background Destruction by oxidation, or oxidative killing, is the most important defense against
surgical pathogens and depends on the partial pressure of oxygen in contaminated tissue…
surgical pathogens and depends on the partial pressure of oxygen in contaminated tissue…
Aspirin in patients undergoing noncardiac surgery
…, K Leslie, P Alonso-Coello, A Kurz… - … England Journal of …, 2014 - Mass Medical Soc
Background There is substantial variability in the perioperative administration of aspirin in
patients undergoing noncardiac surgery, both among patients who are already on an aspirin …
patients undergoing noncardiac surgery, both among patients who are already on an aspirin …
FSP1 is a glutathione-independent ferroptosis suppressor
…, V Mohana, M Rehberg, A Flatley, A Schepers, A Kurz… - Nature, 2019 - nature.com
Ferroptosis is an iron-dependent form of necrotic cell death marked by oxidative damage to
phospholipids 1 , 2 . To date, ferroptosis has been thought to be controlled only by the …
phospholipids 1 , 2 . To date, ferroptosis has been thought to be controlled only by the …
Relationship between intraoperative mean arterial pressure and clinical outcomes after noncardiac surgery: toward an empirical definition of hypotension
Background: Intraoperative hypotension may contribute to postoperative acute kidney injury
(AKI) and myocardial injury, but what blood pressures are unsafe is unclear. The authors …
(AKI) and myocardial injury, but what blood pressures are unsafe is unclear. The authors …
Relationship between intraoperative hypotension, defined by either reduction from baseline or absolute thresholds, and acute kidney and myocardial injury after …
Background How best to characterize intraoperative hypotension remains unclear. Thus, the
authors assessed the relationship between myocardial and kidney injury and intraoperative …
authors assessed the relationship between myocardial and kidney injury and intraoperative …
Opioid-induced bowel dysfunction: pathophysiology and potential new therapies
A Kurz, DI Sessler - Drugs, 2003 - Springer
Opioid treatment for postoperative or chronic pain is frequently associated with adverse effects,
the most common being dose-limiting and debilitating bowel dysfunction. Postoperative …
the most common being dose-limiting and debilitating bowel dysfunction. Postoperative …
Mild intraoperative hypothermia prolongs postanesthetic recovery
…, E Marker, V Goll, H Tschernich, A Kurz… - The Journal of the …, 1997 - pubs.asahq.org
Background Intraoperative hypothermia is common and persists for several hours after
surgery. Hypothermia may prolong immediate recovery by augmenting anesthetic potency, …
surgery. Hypothermia may prolong immediate recovery by augmenting anesthetic potency, …
Heat flow and distribution during induction of general anesthesia
…, AM Sessler, M Schroeder, M Ozaki, A Kurz… - The Journal of the …, 1995 - pubs.asahq.org
Background Core hypothermia after induction of general anesthesia results from an internal
core-to-peripheral redistribution of body heat and a net loss of heat to the environment. …
core-to-peripheral redistribution of body heat and a net loss of heat to the environment. …
Association of postoperative high-sensitivity troponin levels with myocardial injury and 30-day mortality among patients undergoing noncardiac surgery
Importance Little is known about the relationship between perioperative high-sensitivity
troponin T (hsTnT) measurements and 30-day mortality and myocardial injury after noncardiac …
troponin T (hsTnT) measurements and 30-day mortality and myocardial injury after noncardiac …
