Increased anxiety-like behaviors in rats experiencing chronic inflammatory pain
For many patients, chronic pain is often accompanied, and sometimes amplified, by co-morbidities
such as anxiety and depression. Although it represents important challenges, the …
such as anxiety and depression. Although it represents important challenges, the …
The Canadian minimum dataset for chronic low back pain research: a cross-cultural adaptation of the National Institutes of Health Task Force Research Standards
Background: To better standardize clinical and epidemiological studies about the prevalence,
risk factors, prognosis, impact and treatment of chronic low back pain, a minimum data set …
risk factors, prognosis, impact and treatment of chronic low back pain, a minimum data set …
[HTML][HTML] Relationship between blood-and cerebrospinal fluid–bound neurotransmitter concentrations and conditioned pain modulation in pain-free and chronic pain …
Descending pain inhibition is an endogenous pain control system thought to depend partially
on the activation of bulbospinal monoaminergic pathways. Deficits in descending pain …
on the activation of bulbospinal monoaminergic pathways. Deficits in descending pain …
Pain relief devoid of opioid side effects following central action of a silylated neurotensin analog
…, K Kirby, AJ Parent, I Dubuc, N Beaudet, J Côté… - European Journal of …, 2020 - Elsevier
Neurotensin (NT) exerts naloxone-insensitive antinociceptive action through its binding to
both NTS 1 and NTS 2 receptors and NT analogs provide stronger pain relief than morphine …
both NTS 1 and NTS 2 receptors and NT analogs provide stronger pain relief than morphine …
Multicenter assessment of quantitative sensory testing (QST) for the detection of neuropathic-like pain responses using the topical capsaicin model
…, W Gandhi, ML Ma, F Chouchou, AJ Parent… - Canadian Journal of …, 2018 - Taylor & Francis
Background The use of quantitative sensory testing (QST) in multicenter studies has been
quite limited, due in part to lack of standardized procedures among centers. Aim The aim of …
quite limited, due in part to lack of standardized procedures among centers. Aim The aim of …
Preoperative norepinephrine levels in cerebrospinal fluid and plasma correlate with pain intensity after pediatric spine surgery
CE Ferland, AJ Parent, N Saran, PM Ingelmo… - Spine deformity, 2017 - Springer
Purpose Catecholamines were found to be involved in descending pain modulation and
associated with perioperative pain. The purpose of the present study was to investigate the …
associated with perioperative pain. The purpose of the present study was to investigate the …
[HTML][HTML] Prevalence of adolescent problem gambling: A systematic review of recent research
… the DSM-IV-MR-J. Online gambling was associated with significantly higher Internet Addiction
scores, lower parental care, and higher parental overprotection. Individuals with serious …
scores, lower parental care, and higher parental overprotection. Individuals with serious …
Focus on cannabinoids and synthetic cannabinoids
R Le Boisselier, J Alexandre… - Clinical …, 2017 - Wiley Online Library
… Oxidative metabolic patterns of parent compounds are dominated by hydroxylation, … the
parent drug did not.9 However, for most SCs, the contribution of the metabolites is unknown. …
parent drug did not.9 However, for most SCs, the contribution of the metabolites is unknown. …
[HTML][HTML] Parricides: Characteristics of offenders and victims, legal factors, and treatment issues
M Hillbrand, JW Alexandre, JL Young… - Aggression and violent …, 1999 - Elsevier
… literature have presented youths who killed a parent as prosocial individuals who feared
for their lives. Adults who killed a parent have typically been presented as suffering from a …
for their lives. Adults who killed a parent have typically been presented as suffering from a …
Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?
D Trachootham, J Alexandre, P Huang - Nature reviews Drug discovery, 2009 - nature.com
… and hydrogen peroxide levels, were shown to express higher levels of antioxidants such
as peroxiredoxin-3 and thioredoxin peroxidase compared with their non-tumorigenic parental …
as peroxiredoxin-3 and thioredoxin peroxidase compared with their non-tumorigenic parental …