KLHL3 mutations cause familial hyperkalemic hypertension by impairing ion transport in the distal nephron

…, V Probst, C Thauvin, RJ Unwin, SD Soroka… - Nature …, 2012 - nature.com
Familial hyperkalemic hypertension (FHHt) is a Mendelian form of arterial hypertension that
is partially explained by mutations in WNK1 and WNK4 that lead to increased activity of the …

Frailty and mortality in dialysis: evaluation of a clinical frailty scale

…, SD Soroka, BA Kiberd, D Landry… - Clinical Journal of the …, 2015 - journals.lww.com
Results The cohort consisted of 390 patients with completed CFS scores (mean age of 63±15
years old). Most were Caucasian (89%) and men (67%), and 30% of patients had ESRD …

Randomized, controlled trial of darbepoetin alfa for the treatment of anemia in hemodialysis patients

…, SK Swan, JS Lindberg, SD Soroka… - American journal of …, 2002 - Elsevier
Background: Darbepoetin alfa (Aranesp; Amgen, Thousand Oaks, CA) is a new
erythropoiesis-stimulating protein with a threefold longer terminal half-life than recombinant human …

A prospective evaluation of renal replacement therapy modality eligibility

DC Mendelssohn, SK Mujais, SD Soroka… - Nephrology Dialysis …, 2009 - academic.oup.com
Background. Patient eligibility for renal replacement therapy (RRT) modalities is frequently
debated, but little prospective data are available from large patient cohorts. Methods. We …

Canadian Society of Nephrology commentary on the 2012 KDIGO clinical practice guideline for anemia in CKD

…, P McFarlane, L Harwood, MM Sood, SD Soroka… - American Journal of …, 2013 - Elsevier
The KDIGO (Kidney Disease: Improving Global Outcomes) 2012 clinical practice guideline
for anemia management in patients with chronic kidney disease provides the structural and …

Comorbidity burden at dialysis initiation and mortality: A cohort study

…, JP Royston, T Alfaadhel, SD Soroka… - Canadian journal of …, 2015 - journals.sagepub.com
Background: A high level of comorbidity at dialysis initiation is associated with an increased
risk of death. However, contemporary assessments of the validity and prognostic value of …

Canadian society of nephrology commentary on the kidney disease improving global outcomes 2017 clinical practice guideline update for the diagnosis, evaluation …

…, SD Soroka, AJ Vinson, D Zimmerman… - … Journal of Kidney …, 2020 - journals.sagepub.com
… With regard to vitamin D, we suggest against routine screening for vitamin D deficiency in …
population health recommendations for adequate vitamin D intake. We recommend that the …

Vascular access

…, CT Chan, C Deziel, D Hirsch, SD Soroka… - Journal of the …, 2006 - journals.lww.com
Background Arteriovenous (AV) access–related complications result in considerable
morbidity. With a dedicated access team, including a nephrologist, an access surgeon, an …

Macrocytosis may be associated with mortality in chronic hemodialysis patients: a prospective study

KK Tennankore, SD Soroka, KA West, BA Kiberd - BMC nephrology, 2011 - Springer
Background Macrocytosis occurs in chronic hemodialysis (CHD) patients; however, its
significance is unknown. The purpose of this study was to establish the prevalence and …

An evaluation of oral dabigatran etexilate pharmacokinetics and pharmacodynamics in hemodialysis

JAS Wilson, KB Goralski, SD Soroka… - The Journal of …, 2014 - Wiley Online Library
Dabigatran etexilate represents a possible improved alternative to warfarin for anticoagulation
in hemodialysis patients with atrial fibrillation (AF). The objective was to determine …