The brain dead patient is the ideal multiorgan donor. Conversely, brain death (BD) is an undesirable outcome of critical care medicine. Conditions that can lead to the state of BD are limited. An analysis showed that a (aneurysmal) subarachnoid hemorrhage, traumatic brain injury, or intracerebral hemorrhage in 83% precede the state of BD. Because of better prevention and treatment options, we should anticipate on an inescapable and desirable decline of BD. In this article, we offer arguments for this statement and discuss alternatives to maintain a necessary level of donor organs for transplantation.