Patterns in the use of benzodiazepines in British Columbia: examining the impact of increasing research and guideline cautions against long-term use

Health Policy. 2010 Oct;97(2-3):122-9. doi: 10.1016/j.healthpol.2010.03.008. Epub 2010 Apr 21.

Abstract

Objective: We examined changes in patterns of benzodiazepine use in British Columbia over a period of increasing evidence of harms associated with long-term use.

Methods: Using linked administrative databases for the years 1996 and 2006, we performed logistic regression to examine how socio-economic and health factors affect the likelihood of benzodiazepine use and long-term use, and to test for changes in rates of use and long-term use over time.

Results: In 2006, 8.4% of British Columbians used benzodiazepines, 3.5% long-term. Use was positively related with being female, lower income, older, and of poorer health status. Long-term use was positively associated with being in the lowest income quintile, of poorest health, and over the age of 65. While the rate of long-term use decreased from 1996 to 2006 for those over age 70, it increased in middle-aged populations.

Conclusions: Our results suggest, despite increased awareness of and cautions regarding risks associated with long-term use of benzodiazepines, rates of potentially inappropriate use have changed very little over a decade. Given that early use of benzodiazepines is positively associated with later long-term use, policies targeting populations younger than conventionally studied (i.e. those under age 65) may be needed to decrease rates of long-term use.

MeSH terms

  • Adolescent
  • Adult
  • Age Distribution
  • Aged
  • Benzodiazepines*
  • British Columbia
  • Child
  • Child, Preschool
  • Drug Utilization
  • Female
  • Guideline Adherence / trends*
  • Humans
  • Inappropriate Prescribing / trends*
  • Infant
  • Infant, Newborn
  • Likelihood Functions
  • Logistic Models
  • Male
  • Middle Aged
  • Sex Distribution
  • Time Factors

Substances

  • Benzodiazepines