| Treatment comparators | Subgroup | Description | |||
| Genotype 1 | N/NC | N/C | E/NC | E/C | |
| PR48 | X | X | X | X | Pegylated interferon + ribavirin for 48 wk |
| SOF24 + RBV24 | X | X | Sofosbuvir + ribavirin for 24 wk | ||
| SIM12 + SOF12 | X | X | X | X | Simeprevir + sofosbuvir for 12 wk |
| SOF12 + LDV12 | X | X | X | sofosbuvir + ledipasvir for 12 wk | |
| PAR/RIT12 + OMB12 + DAS12 | X | X | Paritaprevir/ritonavir + ombitasvir + dasabuvir for 12 wk | ||
| PAR/RIT12 + OMB12 + DAS12 + RBV12 | X | X | Paritaprevir/ritonavir + ombitasvir + dasabuvir + ribavirin for 12 wk | ||
| DCV12 + SOF12 | X | Daclatasvir and sofosbuvir for 12 wk | |||
| T12 PR24-48 RGT q8 | X | X | Telaprevir for 12 wk and PR used as RGT for 24 or 48 wk (750 mg every 8 h) | ||
| SOF12 + PR12 | X | X | X | X | Sofosbuvir + pegylated interferon + ribavirin for 12 wk |
| SOF12 + PR24-48 RGT | X | Sofosbuvir for 12 wk and PR used as RGT for 24 or 48 wk | |||
| SIM12 + PR24-48 RGT | X | X | X | X | Simeprevir for 12 wk and PR used as RGT for 24 or 48 wk |
| B24 + PR28-48 RGT | X | X | Boceprevir for 24 wk and PR used as RGT for 28 or 48 wk | ||
| SIM12 + SOF12 + RBV12 | X | X | Simeprevir + sofosbuvir+ ribavirin for 12 wk | ||
| SIM12 + PR48 | X | X | Simeprevir for 12 wk and PR for 48 wk | ||
| B32 PR36-48 RGT | X | X | Boceprevir for 32 wk and PR used as RGT for 36 or 48 wk | ||
| SOF24 + LDV24 | X | Sofosbuvir + ledipasvir for 24 wk | |||
| SOF12 + LDV12 + RBV12 | X | Sofosbuvir + ledipasvir + ribavirin for 12 wk | |||
| T12 PR48 q8 | X | X | Telaprevir for 12 wk and PR for 48 wk (750 mg every 8 h) | ||
| Genotype 2 | |||||
| SOF12 + RBV12 | X | X | X | X | sofosbuvir + ribavirin for 12 wk |
| SOF12 + PR12 | X | X | X | Sofosbuvir + pegylated interferon + ribavirin for 12 wk | |
| PR24 | X | X | Pegylated interferon + ribavirin for 24 wk | ||
| SOF16 + RBV16 | X | Sofosbuvir + ribavirin for 16 wk | |||
| Genotype 3 | |||||
| PR48 | X | X | X | X | Pegylated interferon + ribavirin for 48 wk |
| DCV12 + SOF12 | X | X | Daclatasvir and sofosbuvir for 12 wk | ||
| SOF24 + RBV24 | X | X | X | X | Sofosbuvir + ribavirin for 24 wk |
| SOF12 + PR12 | X | X | Sofosbuvir + pegylated interferon + ribavirin for 12 wk | ||
| Genotype 4 | |||||
| PR 48 | X | X | Pegylated interferon + ribavirin for 48 wk | ||
| SOF12 + PR12 | X | sofosbuvir + pegylated interferon + ribavirin for 12 wk | |||
| SOF24 + RBV24 | X | X | X | X | Sofosbuvir + ribavirin for 24 wk |
Note: E/C = treatment-experienced with cirrhosis, E/NC = treatment-experienced without cirrhosis, N/C = treatment-naive with cirrhosis, N/NC = treatment-naive without cirrhosis.