| Characteristic/outcome | Cause of donor brain death | ||
|---|---|---|---|
| Anoxic brain injury (n = 80) | Traumatic brain injury (n = 23) | Stroke (n = 40) | |
| Donor age, median (IQR), yr | 35 (21-52) | 34 (25-52) | 55 (37-59)* |
| Recipient age, median (IQR), yr | 50 (37-59) | 60 (49-71) | 48 (35-61) |
| Cold ischemic time, median (IQR), h | 11.5 (6.7-16) | 12 (8-16) | 13 (10-18) |
| No. (%) with delayed graft function (need for dialysis) | 16 (20) | 2 (9) | 11 (28) |
| No. (%) with functional delayed graft function† | 24 (30) | 3 (13) | 12 (30) |
| Length of hospital stay, median (IQR), d | 11 (8-14) | 8 (7-10) | 11 (8-21) |
| Creatinine level, median (IQR), µmol/L‡ | |||
| Day 3 | 360 (205-476) | 232 (129-358) | 457 (222-536)§ |
| Day 5 | 205 (125-407) | 121 (85-231) | 254 (135-421)§ |
| Day 7 | 146 (105-288) | 108 (79-161) | 210 (125-347) |
| At discharge | 124 (93-186) | 94 (80-137) | 145 (92-170) |
| 1 yr | 105 (87-140) | 98 (73-111) | 124 (98-169) |
| No. (%) who died in hospital | 2 (2) | 0 | 0 |
| No. (%) undergoing dialysis at 1 yr | 1 (1) | 1 (4) | 2 (5) |
*p < 0.05 compared with other categories, analysis of variance with adjustment for multiple comparison.
†Defined as need for dialysis or failure of the creatinine concentration to decrease by 10% or more on 3 or more consecutive days during the week following transplantation.
‡Measured each morning after transplantation.
§p < 0.05 compared with traumatic brain injury with adjustment for multiple comparisons.