Variable | Group; no. (%) of events | Group; rate per 1000 person-years | HR (95% CI)* | ||||||
---|---|---|---|---|---|---|---|---|---|
PPI | Control | PPI | Control | ||||||
Kidney outcomes | |||||||||
Acute kidney injury | 1 269 | (0.4) | 518 | (0.2) | 13.49 | 5.46 | 2.52 (2.27 to 2.79) | ||
Acute interstitial nephritis | 30 | (0.0) | 10 | (0.0) | 0.32 | 0.11 | 3.00 (1.47 to 6.14) | ||
Tracer outcome | |||||||||
Cataract surgery | 4 976 | (1.7) | 5 179 | (1.8) | 53.30 | 55.12 | 0.97 (0.93 to 1.00) |
Note: CI = confidence interval, HR = hazard ratio, PPI = proton pump inhibitor. *Reference group is patients not prescribed a PPI.