Table 3: Clinical and treatment characteristics of Canadian patients presenting with acute ischemic stroke who received thrombolysis during the study period
CharacteristicProportion of patients, %*
Comprehensive stroke centre
n = 297
N, weighted = 1363.8 (66.5%)
Primary stroke centre
n = 162
N, weighted = 569.4 (27.8%)
Other n = 21
N, weighted = 116.3 (5.7%)
Overall
n = 480
N, weighted = 2049.5
Age ≥ 70 yr60.255.173.959.5
Female sex45.445.248.745.5
Hypertension, %67.065.277.367.1
Atrial fibrillation21.416.714.119.7
Diabetes mellitus22.014.315.119.4
Previous stroke16.123.211.517.8
Coronary artery disease31.515.567.229.1
Current smoker15.510.036.416.1
Peripheral vascular disease2.41.318.13.0
Prestroke independence73.871.555.772.1
CNS score ≤ 870.970.955.770.0
Arrival by ambulance96.283.469.791.2
Interval, h, mean ± SE
Onset to arrival3.3 ± 1.1†5.1 ± 0.8†32.2 ± 5.7†5.4 ± 0.8
Arrival to imaging0.7 ± 0.13.4 ± 2.74.41.5 ± 0.7
Onset to treatment4.6 ±1.13.4 ± 0.32.9 ± 0.14.2 ± 0.7
Interval, min, mean ± SE
Imaging to treatment79.0 ± 8.671.9 ± 4.984.477.2 ± 6.3
Arrival to treatment138.1 ± 17.7100.9 ± 15.3112.7 ± 1.9121.1 ± 11.4

Note: CAD = coronary artery disease, CNS = Canadian neurological scale, SE = standard error.
*Unless otherwise stated.
†Statistically significant difference between the 3 groups (p < 0.001). Primary centre compared with comprehensive centre (p = 0.05). Other intervals were not significantly different.