| Characteristic | No. (%) of patients* |
|---|---|
| Median age, yr (range) | 65 (18–102) |
| Male gender | 585 (63.2) |
| Comorbidities | |
| HIV positive or AIDS | 20 (2.2) |
| Intravenous drug use | 163 (17.6) |
| Diabetes mellitus | 250 (27.0) |
| Cardiac disease (coronary artery disease or chronic heart failure) | 244 (26.3) |
| Peripheral vascular disease | 70 (7.6) |
| Cerebrovascular disease | 137 (14.8) |
| Dementia | 53 (5.7) |
| COPD | 84 (9.1) |
| Liver disease | 172 (18.6) |
| Hepatitis B or C co-infection | 54 (5.8) |
| Cirrhosis | 30 (3.2) |
| Pre-existing renal disease | 175 (18.9) |
| Solid malignancy | 171 (18.5) |
| Leukemia and lymphoma | 31 (3.4) |
| Metastatic malignancy | 77 (8.3) |
| Infection characteristics | |
| MRSA | 362 (39.1) |
| Sepsis | 642 (69.4) |
| Dominant focus of infection | |
| Central or peripheral intravascular catheter | 53 (5.8) |
| Pneumonia | 109 (11.8) |
| Skin and soft tissue infection | 175 (18.9) |
| Other† | 10 (1.1) |
Note: COPD = chronic obstructive pulmonary disease, MRSA = methicillin-resistant Staphylococcus aureus. *Unless otherwise indicated. †Includes foci that occur in less than 1% of cases each, such as central nervous system infection (n = 3), lung abscess (n = 3) and urinary tract infection (n = 4).