Table 3: Prescribed targets for the titration of vasopressors*

Variable	% (no.) [95% CI]†				p value
Variable	All sites	Centre 1	Centre 2	Centre 3	p value
No. of patients	369	174	114	81	–
Total no. of targets analyzed	604	277	176	151	–
Patients with ≥ 1 targets	99 (365) [98 to 100]	99 (173) [97 to 100]	99 (113) [95 to 100]	98 (79) [94 to 100]	0.4
All targets‡	n = 604	n = 277	n = 176	n = 151	< 0.001
SAP is only target	16 (95) [13 to 19]	6 (18) [4 to 9]	43 (75) [35 to 49]	1 (2) [0 to 3]
MAP is only target	73 (438) [69 to 76]	79 (220) [75 to 84]	39 (69) [33 to 47]	99 (149) [97 to 100]
SAP and MAP combined	8 (50) [6 to 11]	14 (38) [10 to 18]	7 (12) [3 to 11]	(0)
Other	3 (21) [2 to 5]	0.4 (1) [0 to 2]	11 (20) [7 to 16]	(0)
First target only§	n = 365	n = 173	n = 113	n = 79	< 0.001
SAP is only target	16 (58) [12 to 20]	3 (6) [1 to 6]	45 (51) [36 to 54]	1 (1) [0 to 4]
MAP is only target	75 (273) [70 to 79]	83 (144) [78 to 89]	45 (51) [36 to 54]	99 (78) [96 to 100]
SAP and MAP combined	7 (27) [5 to 10]	13 (23) [8 to 18]	4 (4) [0 to 7]	(0)
Other	2 (7) [1 to 3]	(0)	6 (7) [3 to 12]	(0)
Target value (first targets only)
SAP only, mm Hg, median (IQR)	100 (90 to 100) n = 58	100 (90 to 100) n = 6	100 (90 to 10) n = 51	120 (120 to 120) n = 1	0.04
MAP only, mm Hg, median (IQR)	65 (65 to 70) n = 273	65 (65 to 65) n = 144	65 (65 to 70) n = 51	70 (70 to 75) n = 78	< 0.001

Note: CI = confidence interval, IQR = interquartile range, MAP = mean arterial pressure, SAP = systolic arterial pressure. *Vasopressor targets are values of physiologic variables (e.g., specific blood pressure values) that physicians set as goals of care and achieve by dosing continuous infusions of vasopressors. †Unless stated otherwise. ‡Denominator is total no. of targets analyzed. § Denominator is no. of patients with ≥ 1 targets.