RT Journal Article
SR Electronic
T1 Development of the Canadian COVID-19 Emergency Department Rapid Response Network population-based registry: a methodology study
JF CMAJ Open
JO CMAJ
FD Canadian Medical Association
SP E261
OP E270
DO 10.9778/cmajo.20200290
VO 9
IS 1
A1 Hohl, Corinne M.
A1 Rosychuk, Rhonda J.
A1 McRae, Andrew D.
A1 Brooks, Steven C.
A1 Archambault, Patrick
A1 Fok, Patrick T.
A1 Davis, Philip
A1 Jelic, Tomislav
A1 Turner, Joel P.
A1 Rowe, Brian H.
A1 Mercier, Éric
A1 Cheng, Ivy
A1 Taylor, John
A1 Daoust, Raoul
A1 Ohle, Robert
A1 Andolfatto, Gary
A1 Atzema, Clare
A1 Hayward, Jake
A1 Khangura, Jaspreet K.
A1 Landes, Megan
A1 Lang, Eddy
A1 Martin, Ian
A1 Mohindra, Rohit
A1 Ting, Daniel K.
A1 Vaillancourt, Samuel
A1 Welsford, Michelle
A1 Brar, Baljeet
A1 Dahn, Tara
A1 Wiemer, Hana
A1 Yadav, Krishan
A1 Yan, Justin W.
A1 Stachura, Maja
A1 McGavin, Colleen
A1 Perry, Jeffrey J.
A1 Morrison, Laurie J.
A1 
YR 2021
UL http://www.cmajopen.ca/content/9/1/E261.abstract
AB Background: Emergency physicians lack high-quality evidence for many diagnostic and treatment decisions made for patients with suspected or confirmed coronavirus disease 2019 (COVID-19). Our objective is to describe the methods used to collect and ensure the data quality of a multicentre registry of patients presenting to the emergency department with suspected or confirmed COVID-19.Methods: This methodology study describes a population-based registry that has been enrolling consecutive patients presenting to the emergency department with suspected or confirmed COVID-19 since Mar. 1, 2020. Most data are collected from retrospective chart review. Phone follow-up with patients at 30 days captures the World Health Organization clinical improvement scale and contextual, social and cultural variables. Phone follow-up also captures patient-reported quality of life using the Veterans Rand 12-Item Health Survey at 30 days, 60 days, 6 months and 12 months. Fifty participating emergency departments from 8 provinces in Canada currently enrol patients into the registry.Interpretation: Data from the registry of the Canadian COVID-19 Emergency Department Rapid Response Network will be used to derive and validate clinical decision rules to inform clinical decision-making, describe the natural history of the disease, evaluate COVID-19 diagnostic tests and establish the real-world effectiveness of treatments and vaccines, including in populations that are excluded or underrepresented in clinical trials. This registry has the potential to generate scientific evidence to inform our pandemic response, and to serve as a model for the rapid implementation of population-based data collection protocols for future public health emergencies.Trial registration: Clinicaltrials.gov, no. NCT04702945