RT Journal Article SR Electronic T1 Exploring the approaches of non-Indigenous researchers to Indigenous research: a qualitative study JF CMAJ Open JO CMAJ FD Canadian Medical Association SP E504 OP E509 DO 10.9778/cmajo.20180204 VO 7 IS 3 A1 Alexandra Kilian A1 Tyee Kenneth Fellows A1 Ryan Giroux A1 Jason Pennington A1 Ayelet Kuper A1 Cynthia R. Whitehead A1 Lisa Richardson YR 2019 UL http://www.cmajopen.ca/content/7/3/E504.abstract AB Background: Given the history of unethical research in Indigenous communities, there is often apprehension among Indigenous communities toward research carried out by non-Indigenous researchers. We examined the approaches, experiences and motivations among non-Indigenous researchers at a research-intensive Canadian university conducting research with Indigenous communities to understand approaches to ethical research with Indigenous peoples.Methods: We performed a critical constructivist qualitative study incorporating decolonizing methodologies. We conducted semistructured interviews with 8 non-Indigenous University of Toronto researchers with a research focus/interest related to Indigenous health between August and October 2017. The interviews were transcribed and thematically analyzed through an iterative process. Shared experiences among the researchers were arranged into primary themes.Results: We identified 4 primary themes related to the conduct of Indigenous research by non-Indigenous researchers: 1) relationships with communities are foundational to the research process, 2) non-Indigenous researchers experience a personal self-reflective journey grounded in reconciliation, allyship and privilege, 3) accepted knowledge frameworks in Indigenous research are familiar to most but are inconsistently applied and 4) institutions act as barriers to and facilitators of ethical conduct of Indigenous research. Four core principles — relationships, trust, humility and accountability — unified the primary themes.Interpretation: We identified strengths and areas for improvement of current policies and practices in Indigenous research by non-Indigenous researchers. Although non-Indigenous researchers value relationships, and their research is informed by Indigenous knowledge, institutional barriers to implementing recommended elements exist, and certain policy statements such as the Tri-Council Policy Statement 2 lack applicability to secondary data analysis for some non-Indigenous researchers.